OVGP1 - oviductal glycoprotein 1 Gene

Homo sapiens

Also known as EGP; OGP; MUC9; CHIT5

Gene ID: 5016 | Gene type: protein coding

About OVGP1

Cytogenetic location: 1p13.2 Genomic coordinates (GRCh38): 1:111,414,319-111,427,735 (from NCBI)

This gene has 3 transcripts (splice variants), 139 orthologues and 6 paralogues. Broad expression in endometrium (RPKM 11.4), testis (RPKM 3.0) and 16 other tissues.

Summary

This gene encodes a large, carbohydrate-rich, epithelial glycoprotein with numerous O-glycosylation sites located within threonine, serine, and proline-rich tandem repeats. The gene is similar to members of the Mucin and the glycosyl hydrolase 18 gene families. Regulation of expression may be estrogen-dependent. Gene expression and protein secretion occur during late follicular development through early cleavage-stage embryonic development. The protein is secreted from non-ciliated oviductal epithelial cells and associates with ovulated oocytes, blastomeres, and spermatozoan acrosomal regions. [provided by RefSeq, Jul 2008]

OVGP1 Products(1)

mRNA	Protein	Name
NM_002557.4	NP_002548.3	oviduct-specific glycoprotein precursor

OVGP1 Protein Structure

Glyco_hydro_18

0
200
400
600
678 a.a.

Protein Preferred Names

Protein Names

oviduct-specific glycoprotein

estrogen-dependent oviduct protein

Related Diseases

Diseases

Alias

Chronic Salpingitis

Acute Salpingitis

Anterior Scleritis

Taylor'S Syndrome

Pelvic Congestion Syndrome	Congestion-Fibrosis Syndrome
Taylor Syndrome

Endosalpingiosis

Alveolar Echinococcosis

Echinococcus Multilocularis Infection	Echinococcosis
Alveolococcosis	Multilocular Hydatid
Small Fox Tapeworm

Infectious Anterior Uveitis

Secondary Infected Iridocyclitis	Infectious Secondary Iridocyclitis
Secondary Iridocyclitis, Infectious

Osteoporosis

Postmenopausal Osteoporosis	Osteoporosis, Postmenopausal
Bone Mineral Density Quantitative Trait Locus	Bmnd
Osteoporosis, Involutional	Osteoporosis, Susceptibility To
Osteoporosis, Postmenopausal, Susceptibility	Bone Mineral Density Variation Qtl, Osteoporosis
OSTEOP	Involutional Osteoporosis
Senile Osteoporosis	Osteoporosis Postmenopausal
Bone Mineral Density, Quantitative Trait Locus	Osteoporosis, Senile
Idiopathic Osteoporosis	Bone Rarefaction Nos
Type 1 Osteoporosis

Salpingitis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-108560	(+)-Fluprostenol	Activator	97.00%	Unkown
HY-108560A	15(S)-Fluprostenol	Activator	/	Unkown
HY-RS09882	OVGP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	OVGP1	VGNC	VGNC:75727
Canis familiaris	OVGP1	VGNC	VGNC:84865
Mus musculus	OVGP1	MGD	MGI:106661

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