CNTN3 - contactin 3 Gene
Also Known as PCS; PANG; BIG-1
Species: Homo sapiens
About CNTN3
This gene has 2 transcripts (splice variants), 124 orthologues and 36 paralogues. Broad expression in brain (RPKM 2.7), prostate (RPKM 1.8) and 18 other tissues.
Summary
Predicted to be involved in cell adhesion and nervous system development. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in neuron projection. [provided by Alliance of Genome Resources, Apr 2022]
CNTN3 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001393376.1 | NP_001380305.1 | contactin-3 precursor |
| NM_020872.3 | NP_065923.1 | contactin-3 precursor |
CNTN3 Protein Structure
I-set: Immunoglobulin I-set domain (40 - 116)
Ig_2: Immunoglobulin domain (131 - 201)
I-set: Immunoglobulin I-set domain (232 - 309)
I-set: Immunoglobulin I-set domain (319 - 403)
I-set: Immunoglobulin I-set domain (409 - 496)
I-set: Immunoglobulin I-set domain (501 - 594)
fn3: Fibronectin type III domain (600 - 687)
fn3: Fibronectin type III domain (704 - 790)
fn3: Fibronectin type III domain (805 - 891)
fn3: Fibronectin type III domain (906 - 986)
- 0
- 200
- 400
- 600
- 800
- 1028 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
contactin-3 |
|
Recombinant CNTN3 Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P72947 | Contactin-3/CNTN3 Protein, Human (N708D, HEK293, Fc) | Q9P232/NP_065923.1 (E20-S1002, N708D) | ≥ 90%, as determined by reducing SDS-PAGE. |
| HY-P74229 | Contactin-3/CNTN3 Protein, Human (N708D, HEK293, His) | Q9P232/NP_065923.1 (E20-S1002, N708D) | ≥ 95%, as determined by reducing SDS-PAGE. |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Plasmacytoma |
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| Pilocytic Astrocytoma Of Cerebellum |
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| Cerebellar Astrocytoma |
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| Chromosome 3pter-P25 Deletion Syndrome |
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| Pneumonic Tularemia |
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| Miles-Carpenter Syndrome |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | CNTN3 | MGD | MGI:99534 |
| Felis catus | CNTN3 | VGNC | VGNC:97386 |
| Bos taurus | CNTN3 | VGNC | VGNC:27538 |
| Canis familiaris | CNTN3 | VGNC | VGNC:39434 |
| Macaca mulatta | CNTN3 | VGNC | VGNC:71285 |
| Rattus norvegicus | CNTN3 | RGD | RGD:3253 |
| Others | CNTN3 | NCBI |