Dkk3 - dickkopf WNT signaling pathway inhibitor 3 Gene

Also Known as dkk-3; mDkk-3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 50781

Summary

Predicted to enable co-receptor binding activity and receptor antagonist activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway and negative regulation of cellular biosynthetic process. Predicted to act upstream of or within Wnt signaling pathway. Located in extracellular space. Is expressed in several structures, including brain; cardiovascular system; eye; limb; and tooth. Orthologous to human DKK3 (dickkopf Wnt signaling pathway inhibitor 3). [provided by Alliance of Genome Resources, Apr 2022]

Dkk3 Products (4)

mRNA Protein Name
NM_001360257.1 NP_001347186.1 dickkopf-related protein 3 isoform a precursor
NM_001360260.1 NP_001347189.1 dickkopf-related protein 3 isoform b precursor
NM_001360261.1 NP_001347190.1 dickkopf-related protein 3 isoform c precursor
NM_015814.3 NP_056629.1 dickkopf-related protein 3 isoform b precursor
Protein Preferred Names Protein Names

dickkopf-related protein 3

  • dickkopf homolog 3

  • dickkopf-3

Recombinant Dkk3 Proteins

Cat. No. Product Name Accession Purity
HY-P75287 DKK-3 Protein, Mouse (HEK293, His) Q9QUN9 (P23-I349) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W107409 Meridianin C 99.68% Unkown
HY-179459 SJ-300 Inhibitor / Unkown
HY-RS03789 DKK3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16965 Dkk3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23408 Dkk3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990250 Anti-Mouse DKK3 Antibody (DKK3-4.22) 95.00% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dkk3 NCBI NCBI:27122