TAS2R7 - taste 2 receptor member 7 Gene

Also Known as T2R7; TRB4

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 50837

About TAS2R7

Cytogenetic location: 12p13.2 Genomic coordinates (GRCh38): 12:10,801,532-10,802,627 (from NCBI)

This gene has 1 transcript (splice variant), 1 gene allele, 164 orthologues and 23 paralogues.

Summary

This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the Taste Receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the Taste Receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008]

TAS2R7 Products (1)

mRNA Protein Name
NM_023919.2 NP_076408.1 taste receptor type 2 member 7

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables bitter taste receptor activity IDA
IDA: Inferred from direct assay
20022913 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
33961781 GOA
Biological Process GO Annotation Evidence References Source
involved in detection of chemical stimulus involved in sensory perception of bitter taste IDA
IDA: Inferred from direct assay
20022913 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TAS2R7 Protein Structure

TAS2R

TAS2R: Taste receptor protein (TAS2R) (1 - 303)

  • 0
  • 100
  • 200
  • 300
  • 318 a.a.
Protein Preferred Names Protein Names

taste receptor type 2 member 7

  • taste receptor, family B, member 4

TAS2R7 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TAS2R7 Q9NYW3 ATP2B4 Homo sapiens P23634
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14220 TAS2R7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TAS2R7 RGD RGD:1597354
Bos taurus TAS2R7 VGNC VGNC:109397
Mus musculus TAS2R7 MGD MGI:2681278
Canis familiaris TAS2R7 VGNC VGNC:47121
Others TAS2R7 NCBI