Tnfsf14 - tumor necrosis factor (ligand) superfamily, member 14 Gene

Also Known as LTg; HVEML; LIGHT; Ly113; HVEM-L; Tnlg1d

Species: Mus musculus

Gene Type: protein coding
Gene ID: 50930

Summary

Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process; identical protein binding activity; and signaling receptor binding activity. Acts upstream of or within several processes, including T cell costimulation; positive regulation of T cell chemotaxis; and positive regulation of myoblast fusion. Predicted to be located in plasma membrane. Used to study IgA glomerulonephritis. Orthologous to human TNFSF14 (TNF Superfamily member 14). [provided by Alliance of Genome Resources, Apr 2022]

Tnfsf14 Products (1)

mRNA Protein Name
NM_019418.4 NP_062291.1 tumor necrosis factor ligand superfamily member 14

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
27152329 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of T cell chemotaxis IDA
IDA: Inferred from direct assay
21236258 MGI
acts upstream of or within T cell costimulation IDA
IDA: Inferred from direct assay
15568026 MGI
acts upstream of or within positive regulation of T cell chemotaxis IDA
IDA: Inferred from direct assay
21236258 MGI
acts upstream of or within positive regulation of myoblast differentiation IMP
IMP: Inferred from mutant phenotype
23844157 MGI
acts upstream of or within positive regulation of myoblast fusion IMP
IMP: Inferred from mutant phenotype
23844157 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tumor necrosis factor ligand superfamily member 14

  • tumor necrosis factor ligand 1d

Recombinant Tnfsf14 Proteins

Cat. No. Product Name Accession Purity
HY-P73837 LIGHT/TNFSF14 Protein, Mouse (sf9, His) NP_062291.1 (D72-V239) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P73837A LIGHT/TNFSF14 Protein, Mouse (sf9, His, solution) Q9QYH9 (D72-V239) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P700221AF Animal-Free LIGHT/TNFSF14 Protein, Mouse (His) Q9QYH9 (R58-V239) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14825 TNFSF14 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17029 Tnfsf14 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23473 Tnfsf14 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P99810 Quisovalimab 98.73% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnfsf14 NCBI NCBI:8740