CSAD - cysteine sulfinic acid decarboxylase Gene

Also Known as CSD; PCAP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51380

About CSAD

Cytogenetic location: 12q13.13 Genomic coordinates (GRCh38): 12:53,157,663-53,181,351 (from NCBI)

This gene has 19 transcripts (splice variants), 201 orthologues and 7 paralogues. Ubiquitous expression in fat (RPKM 9.9), skin (RPKM 8.5) and 25 other tissues.

Summary

This gene encodes a member of the group 2 decarboxylase family. A similar protein in rodents plays a role in multiple biological processes as the rate-limiting enzyme in taurine biosynthesis, catalyzing the decarboxylation of cysteinesulfinate to hypotaurine. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

CSAD Products (3)

mRNA Protein Name
NM_001244705.2 NP_001231634.1 cysteine sulfinic acid decarboxylase isoform 2
NM_001244706.2 NP_001231635.1 cysteine sulfinic acid decarboxylase isoform 3
NM_015989.5 NP_057073.4 cysteine sulfinic acid decarboxylase isoform 1

CSAD Protein Structure

Pyridoxal_deC

Pyridoxal_deC: Pyridoxal-dependent decarboxylase conserved domain (49 - 416)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 493 a.a.
Protein Preferred Names Protein Names

cysteine sulfinic acid decarboxylase

  • P-selectin cytoplasmic tail-associated protein

Related Diseases

Diseases Alias
Stiff-Person Syndrome

  • SPS

  • Stiff-Man Syndrome

  • Stiff Man Syndrome

  • Stiff Person Syndrome

  • Moersch-Woltman Syndrome

  • Sms

  • Stiff-Trunk Syndrome

  • Morsch Woltman Syndrome

  • Stiff Person Syndrome And Related Disorders

  • Stiff Person Spectrum Disorder

  • Classic Stiff Person Syndrome

  • Classic Sps

  • Focal Stiff Limb Syndrome

  • Focal Stiff-Person Syndrome

  • Stiff Leg Syndrome

  • Progressive Encephalomyelitis With Rigidity
Autoimmune Disease

  • Autoimmune Diseases

  • Autoimmune Hypersensitivity Disease

  • Hypersensitivity Reaction Type Ii Disease

  • Type Ii Hypersensitivity Reaction Disease
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03222 CSAD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19125 Csad Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25615 Csad Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris CSAD VGNC VGNC:39649
Felis catus CSAD VGNC VGNC:61212
Bos taurus CSAD VGNC VGNC:27749
Mus musculus CSAD MGD MGI:2180098
Macaca mulatta CSAD VGNC VGNC:71439
Rattus norvegicus CSAD RGD RGD:621030
Others CSAD NCBI