CSAD - cysteine sulfinic acid decarboxylase Gene

Homo sapiens

Also known as CSD; PCAP

Gene ID: 51380 | Gene type: protein coding

About CSAD

Cytogenetic location: 12q13.13 Genomic coordinates (GRCh38): 12:53,157,663-53,181,351 (from NCBI)

This gene has 19 transcripts (splice variants), 201 orthologues and 7 paralogues. Ubiquitous expression in fat (RPKM 9.9), skin (RPKM 8.5) and 25 other tissues.

Summary

This gene encodes a member of the group 2 decarboxylase family. A similar protein in rodents plays a role in multiple biological processes as the rate-limiting Enzyme in taurine biosynthesis, catalyzing the decarboxylation of cysteinesulfinate to hypotaurine. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

CSAD Products(3)

mRNA	Protein	Name
NM_001244705.2	NP_001231634.1	cysteine sulfinic acid decarboxylase isoform 2
NM_001244706.2	NP_001231635.1	cysteine sulfinic acid decarboxylase isoform 3
NM_015989.5	NP_057073.4	cysteine sulfinic acid decarboxylase isoform 1

CSAD Protein Structure

Pyridoxal_deC

0
100
200
300
400
493 a.a.

Protein Preferred Names

Protein Names

cysteine sulfinic acid decarboxylase

P-selectin cytoplasmic tail-associated protein

Related Diseases

Diseases

Alias

Stiff-Person Syndrome

SPS	Stiff-Man Syndrome
Stiff Man Syndrome	Stiff Person Syndrome
Moersch-Woltman Syndrome	Sms
Stiff-Trunk Syndrome	Morsch Woltman Syndrome
Stiff Person Syndrome And Related Disorders	Stiff Person Spectrum Disorder
Classic Stiff Person Syndrome	Classic Sps
Focal Stiff Limb Syndrome	Focal Stiff-Person Syndrome
Stiff Leg Syndrome	Progressive Encephalomyelitis With Rigidity

Autoimmune Disease

Autoimmune Diseases	Autoimmune Hypersensitivity Disease
Hypersensitivity Reaction Type Ii Disease	Type Ii Hypersensitivity Reaction Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03222	CSAD Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	CSAD	VGNC	VGNC:39649
Felis catus	CSAD	VGNC	VGNC:61212
Bos taurus	CSAD	VGNC	VGNC:27749
Mus musculus	CSAD	MGD	MGI:2180098
Macaca mulatta	CSAD	VGNC	VGNC:71439
Rattus norvegicus	CSAD	RGD	RGD:621030
Others	CSAD	NCBI