PRMT5 - protein arginine methyltransferase 5 Gene

Also Known as SKB1

Species: Bos taurus

Gene Type: protein coding
Gene ID: 515594

About PRMT5

Primary_assembly 10: 21,915,369-21,923,670 forward strand.ARS-UCD1.2:CM008177.2

This gene has 2 transcripts (splice variants) and 200 orthologues.

PRMT5 Products (1)

mRNA Protein Name
NM_001105374.1 NP_001098844.1 protein arginine N-methyltransferase 5

PRMT5 Protein Structure

PRMT5_TIM

PRMT5_TIM: pfam17285 (36 - 289)

PRMT5

PRMT5: pfam05185 (294 - 463)

PRMT5_C

PRMT5_C: pfam17286 (467 - 634)

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  • 200
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  • 500
  • 600
  • 637 a.a.
Protein Preferred Names Protein Names

protein arginine N-methyltransferase 5

  • SKB1 homolog

  • histone-arginine N-methyltransferase PRMT5

  • shk1 kinase-binding protein 1 homolog

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-101563 GSK3326595 Inhibitor 99.83% Phase 2
HY-101564 Onametostat Inhibitor 99.79% Phase 1
HY-131493 PF-06939999 Inhibitor 99.84% Phase 1

Pre-clinical Phase

Bioactive Molecules (54)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-139611 Navlimetostat Inhibitor 99.28% Unkown
HY-12727 EPZ015666 Inhibitor 99.86% Unkown
HY-100235 GSK591 Inhibitor 99.91% Unkown
HY-107777 LLY-283 Inhibitor 98.93% Unkown
HY-148419 Ralometostat Inhibitor 99.90% Unkown
HY-141877 MS4322 Degrader 99.14% Unkown
HY-124131 DS-437 Inhibitor 99.22% Unkown
HY-100025A HLCL-61 hydrochloride Inhibitor 99.87% Unkown
HY-132309 BRD0639 Inhibitor 98.04% Unkown
HY-138684 MRTX9768 Inhibitor 99.60% Unkown
HY-139611C Navlimetostat hydrochloride Inhibitor 99.61% Unkown
HY-148674 AM-9747 Inhibitor 99.76% Unkown
HY-109963 PR5-LL-CM01 Inhibitor 98.37% Unkown
HY-Q36691 PRMT5-IN-30 Inhibitor 99.35% Unkown
HY-139611B (S)-Navlimetostat Inhibitor 98.15% Unkown
HY-141877B MS4322 (isomer) 99.87% Unkown
HY-120137 CMP-5 Inhibitor 99.61% Unkown
HY-128579 DW14800 Inhibitor 99.12% Unkown
HY-126256A PRMT5-IN-1 hydrochloride Inhibitor 99.51% Unkown
HY-W072962 WX2-43 Inhibitor 98.74% Unkown
HY-111213 PRMT5-IN-20 Inhibitor 99.20% Unkown
HY-126256 PRMT5-IN-1 Inhibitor / Unkown
HY-138684A MRTX9768 hydrochloride Inhibitor 99.88% Unkown
HY-158143 AZD3470 Inhibitor 99.74% Unkown
HY-182820 YZ-836P / Unkown
HY-134883 PRMT5-IN-4 Inhibitor 99.0% Unkown
HY-141876 PRT543 Inhibitor / Unkown
HY-182892 MC4491 Inhibitor / Unkown
HY-168842 PRMT5-IN-47 Inhibitor / Unkown
HY-162230 PRMT5-IN-33 Inhibitor / Unkown
HY-169708 PRMT5-IN-49 Inhibitor / Unkown
HY-161334 CARM1-IN-4 Inhibitor / Unkown
HY-146810 PRMT4-IN-1 Inhibitor / Unkown
HY-153421 PRMT5-IN-28 Inhibitor / Unkown
HY-163593 PRMT5-IN-44 Inhibitor / Unkown
HY-181522 PRMT5 ligand 3 Ligand / Unkown
HY-173092 PRMT5 ligand 1 Ligand / Unkown
HY-149005 PRMT5-IN-19 Inhibitor / Unkown
HY-178028 PRMT5-IN-53 Inhibitor / Unkown
HY-150081 PRMT5-IN-21 Inhibitor / Unkown
HY-163587 PRMT5-IN-39-d3 Inhibitor / Unkown
HY-175821 PRMT1-IN-3 Inhibitor / Unkown
HY-163799 PRMT5-MTA-IN-1 Inhibitor / Unkown
HY-P3822 PRMT5-IN-23 Inhibitor / Unkown
HY-180356 PRMT5-IN-54 Inhibitor / Unkown
HY-132937 PRMT5-IN-9 Inhibitor / Unkown
HY-176534 PRMT5-IN-52 Inhibitor / Unkown
HY-176702 PRMT5-MTA-IN-5 Inhibitor / Unkown
HY-176701 PRMT5-MTA-IN-4 Inhibitor / Unkown
HY-163592 PRMT5-IN-43 Inhibitor / Unkown
HY-183951 TNG456 Inhibitor / Unkown
HY-181521 RAPRMT5 Degrader / Unkown
HY-168263 PRMT5-IN-45 Inhibitor / Unkown
HY-163591 PRMT5-IN-36-d3 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PRMT5 NCBI NCBI:10419