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Cat. No.: HY-163591

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PRMT5-IN-36-d₃

PRMT5-IN-36-d3 is the deuterated derivative of PRMT5-IN-36. PRMT5-IN-36-d3 (compound 4) is an orally active PRMT5 inhibitor for cancer research.

For research use only. We do not sell to patients.

CAS No.: 3034034-10-8
Formula: C₂₁H₁₂D₃F₄N₅O₂
Molecular Weight:448.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

PRMT5-IN-36-d₃ Chemical Structure

CAS No.: 3034034-10-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Application
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

PRMT5-IN-36-d3 is the deuterated derivative of PRMT5-IN-36. PRMT5-IN-36-d3 (compound 4) is an orally active PRMT5 inhibitor for cancer research^[1].

IC₅₀ & Target

PRMT5

All Histone Methyltransferase Isoforms :

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 3034034-10-8
Unlabeled Cas 3034033-98-9
Molecular Weight 448.39
Formula C₂₁H₁₂D₃F₄N₅O₂
SMILES

[2H]C([2H])([2H])N([C@H]1C2=CC=C(C(F)(F)F)C=C2OC1)C(C3=C(F)C=C4N=C(N)C5=CN=CN5C4=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yao Bing, et al. Novel prmt5 inhibitor and use thereof. WO2024067433A1. 2024-04-04

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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- IC₅₀ & Target
- Application
Chemical Information
Purity & Documentation
References

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PRMT5-IN-36-d3

All Histone Methyltransferase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

PRMT5-IN-36-d3 Related Classifications

HY-163591 Related Classifications

PRMT5-IN-36-d₃

PRMT5-IN-36-d₃ Related Classifications