FKBP7 - FKBP prolyl isomerase 7 Gene

Also Known as FKBP23; PPIase

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51661

About FKBP7

Cytogenetic location: 2q31.2 Genomic coordinates (GRCh38): 2:178,463,664-178,478,600 (from NCBI)

This gene has 12 transcripts (splice variants), 210 orthologues and 18 paralogues. Broad expression in ovary (RPKM 13.6), endometrium (RPKM 9.0) and 21 other tissues.

Summary

The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. Members of this family exhibit PPIase activity and function as molecular chaperones. A similar protein in mouse is located in the endoplasmic reticulum and binds calcium. [provided by RefSeq, Jul 2008]

FKBP7 Products (3)

mRNA Protein Name
NM_001135212.2 NP_001128684.1 peptidyl-prolyl cis-trans isomerase FKBP7 isoform b precursor
NM_001410972.1 NP_001397901.1 peptidyl-prolyl cis-trans isomerase FKBP7 isoform c precursor
NM_181342.3 NP_851939.1 peptidyl-prolyl cis-trans isomerase FKBP7 isoform a precursor

FKBP7 Protein Structure

FKBP_C

FKBP_C: FKBP-type peptidyl-prolyl cis-trans isomerase (48 - 141)

EF-hand_7

EF-hand_7: EF-hand domain pair (153 - 215)

  • 0
  • 100
  • 200
  • 222 a.a.
Protein Preferred Names Protein Names

peptidyl-prolyl cis-trans isomerase FKBP7

  • 23 kDa FK506-binding protein

FKBP7 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
FKBP7 Q9Y680 NPFFR2 Homo sapiens Q9Y5X5-3
Y2H Prey Pooling
32296183
Intra
FKBP7 Q9Y680 NPFFR2 Homo sapiens Q9Y5X5-3
Y2H Array
32296183
Intra
FKBP7 Q9Y680 SGTA Homo sapiens O43765
Y2H Prey Pooling
25416956
Intra
FKBP7 Q9Y680 SGTA Homo sapiens O43765
Y2H Prey Pooling
32296183
Intra
FKBP7 Q9Y680 SGTA Homo sapiens O43765
Y2H Array
32296183
Intra
FKBP7 Q9Y680 PEX19 Homo sapiens P40855
Y2H Array
25416956
Intra
FKBP7 Q9Y680 TMEM108 Homo sapiens Q6UXF1
Y2H Array
32296183
Intra
FKBP7 Q9Y680 TMEM108 Homo sapiens Q6UXF1
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant FKBP7 Proteins

Cat. No. Product Name Accession Purity
HY-P70949 FKBP7 Protein, Human (HEK293, His) Q9Y680-2 (Q24-L222) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P76932 FKBP7 Protein, Human (HEK293, Fc) Q9Y680-2 (Q24-Q218) ≥ 90%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Osteogenesis Imperfecta, Type Xi

  • Osteogenesis Imperfecta Type 11

  • OI11

  • Osteogenesis Imperfecta Type Xi

  • Oi, Type Xi

  • Osteogenesis Imperfecta 11

  • Oi Type Xi

  • Oi-Xi
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04967 FKBP7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20407 Fkbp7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26916 Fkbp7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus FKBP7 RGD RGD:1305293
Macaca mulatta FKBP7 VGNC VGNC:72667
Felis catus FKBP7 VGNC VGNC:62283
Bos taurus FKBP7 VGNC VGNC:29026
Mus musculus FKBP7 MGD MGI:1336879
Canis familiaris FKBP7 VGNC VGNC:40893
Others FKBP7 NCBI