Nucb2 - nucleobindin 2 Gene

Also Known as Nefa; Calnuc; Nesfatin-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 53322

Summary

Enables calcium ion binding activity. Predicted to be involved in several processes, including negative regulation of appetite; negative regulation of cell communication; and positive regulation of testosterone secretion. Predicted to act upstream of or within cellular calcium ion homeostasis. Located in endoplasmic reticulum and nuclear outer membrane. Is expressed in several structures, including extraembryonic component and female reproductive system. Orthologous to human NUCB2 (nucleobindin 2). [provided by Alliance of Genome Resources, Apr 2022]

Nucb2 Products (2)

mRNA Protein Name
NM_001130479.2 NP_001123951.1 nucleobindin-2 precursor
NM_001360375.1 NP_001347304.1 nucleobindin-2 precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium ion binding IDA
IDA: Inferred from direct assay
10915798 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
10915798 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
10915798 MGI
located in nuclear outer membrane IDA
IDA: Inferred from direct assay
10915798 MGI
located in nucleus IDA
IDA: Inferred from direct assay
10915798 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nucleobindin-2

  • DNA-binding protein NEFA

  • prepronefastin

  • prepronesfatin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09655 NUCB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18672 Nucb2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25158 Nucb2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nucb2 NCBI NCBI:4925