Pgrmc1 - progesterone receptor membrane component 1 Gene

Also Known as mPR; PPMR; Vema; HPR6.6

Species: Mus musculus

Gene Type: protein coding
Gene ID: 53328

Summary

Enables heme binding activity. Predicted to be involved in several processes, including heme biosynthetic process; learning or memory; and positive regulation of protein localization to plasma membrane. Located in mitochondrial outer membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study non-alcoholic fatty liver disease. Orthologous to human PGRMC1 (Progesterone Receptor membrane component 1). [provided by Alliance of Genome Resources, Apr 2022]

Pgrmc1 Products (1)

mRNA Protein Name
NM_016783.4 NP_058063.2 membrane-associated progesterone receptor component 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables heme binding IDA
IDA: Inferred from direct assay
31748741 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
31748741 MGI
Cellular Component GO Annotation Evidence References Source
located in mitochondrial outer membrane IDA
IDA: Inferred from direct assay
27599036 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

membrane-associated progesterone receptor component 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-115625 AG-205 99% Unkown
HY-116968 JVW-1009 Antagonist / Unkown
HY-119386 SAS-0132 / Unkown
HY-120008 SAS-1121 Ligand / Unkown
HY-121012 (rac)-AG-205 / Unkown
HY-RS10399 PGRMC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20577 Pgrmc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27085 Pgrmc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pgrmc1 NCBI NCBI:10857