PLXNB1 - plexin B1 Gene

Homo sapiens

Also known as SEP; PLXN5; PLEXIN-B1

Gene ID: 5364 | Gene type: protein coding

About PLXNB1

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:48,403,854-48,430,310 (from NCBI)

This gene has 19 transcripts (splice variants), 276 orthologues and 8 paralogues. Ubiquitous expression in skin (RPKM 13.8), kidney (RPKM 13.0) and 24 other tissues.

Summary

Enables semaphorin receptor activity. Involved in several processes, including negative regulation of cell adhesion; regulation of cell shape; and semaphorin-plexin signaling pathway. Is integral component of plasma membrane. Part of semaphorin receptor complex. [provided by Alliance of Genome Resources, Apr 2022]

PLXNB1 Products(2)

mRNA	Protein	Name
NM_001130082.3	NP_001123554.1	plexin-B1 precursor
NM_002673.6	NP_002664.2	plexin-B1 precursor

PLXNB1 Protein Structure

Sema

PSI

TIG

Plexin_cytopl

0
400
800
1200
1600
2000
2135 a.a.

Protein Preferred Names

Protein Names

plexin-B1

plexin 5

Recombinant PLXNB1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P79042	Plexin B1 Protein, Human (RRRR1302-1305AAAA, HEK293, His)	O43157 (L20-Q1490, RRRR1302-1305AAAA)	≥95%
HY-P79052	Plexin B1 (Sema domain) Protein, Human (CHO, His)	O43157 (L20-Q535)	≥95%
HY-P700428	Plexin B1 Protein, Human (HEK293, mFc)	O43157 (L20-Q535)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10752	PLXNB1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	PLXNB1	VGNC	VGNC:76187
Felis catus	PLXNB1	VGNC	VGNC:68918
Bos taurus	PLXNB1	VGNC	VGNC:33061
Canis familiaris	PLXNB1	VGNC	VGNC:44722
Mus musculus	PLXNB1	MGD	MGI:2154238
Rattus norvegicus	PLXNB1	RGD	RGD:1310564
Others	PLXNB1	NCBI

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