2. Gene
  3. Car2 - carbonic anhydrase 2 Gene

Car2 - carbonic anhydrase 2 Gene

  • Gene
  • Protein
  • Agent
Rattus norvegicus

Also known as Ca2

Gene ID: 54231 | Gene type: protein coding

About Car2

Primary_assembly 2: 86,741,626-86,756,818 reverse strand.mRatBN7.2:CM026975.1

This gene has 2 transcripts (splice variants), 285 orthologues, 16 paralogues and is associated with 11 phenotypes. Biased expression in Spleen (RPKM 2474.6), Kidney (RPKM 1633.5) and 3 other tissues.

Summary

Enables carbonate dehydratase activity. Involved in several processes, including positive regulation of bone resorption; positive regulation of cellular pH reduction; and positive regulation of osteoclast differentiation. Located in several cellular components, including apical part of cell; basolateral plasma membrane; and microvillus. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 3 and osteopetrosis. Orthologous to human CA2 (Carbonic Anhydrase 2). [provided by Alliance of Genome Resources, Apr 2022]

Car2 Products(1)

mRNA Protein Name
NM_019291.1 NP_062164.1 carbonic anhydrase 2

Car2 Protein Structure

alpha_CA

alpha_CA: cl00012 (0 - 258)

  • 0
  • 100
  • 200
  • 260 a.a.
Protein Preferred Names Protein Names

carbonic anhydrase 2

CA-II

carbonate dehydratase II

carbonic anhydrase II

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01909 Car2 Mouse Pre-designed siRNA Set A / Unkown
HY-RS01910 Car2 Rat Pre-designed siRNA Set A / Unkown
HY-RS01934 CARS2 Human Pre-designed siRNA Set A / Unkown