2. Immunology/Inflammation Stem Cell/Wnt MAPK/ERK Pathway
  3. Interleukin Related ERK
  4. Glutathione trisulfide

Glutathione trisulfide (GSSSG) is a potent neuroprotective agent with anti-inflammatory activity. Glutathione trisulfide prevents the LPS (HY-D1056)-induced inflammatory gene expression in retinal pigment epithelial cells, which is mediated through hyperactivation of ERK signaling, independent of the NRF2/HMOX1 pathway. Glutathione trisulfide can be used for neurodegenerative diseases and ischemic spinal cord injury (SCI) research.

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Glutathione trisulfide

Glutathione trisulfide Chemical Structure

CAS No. : 32607-79-7

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Glutathione trisulfide Related Antibodies

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Description

Glutathione trisulfide (GSSSG) is a potent neuroprotective agent with anti-inflammatory activity. Glutathione trisulfide prevents the LPS (HY-D1056)-induced inflammatory gene expression in retinal pigment epithelial cells, which is mediated through hyperactivation of ERK signaling, independent of the NRF2/HMOX1 pathway. Glutathione trisulfide can be used for neurodegenerative diseases and ischemic spinal cord injury (SCI) research[1][2].

IC50 & Target[1]

IL-6

 

IL-1β

 

Molecular Weight

644.69

Formula

C20H32N6O12S3
CAS No.
SMILES

[C@@H](NC(CC[C@@H](C(O)=O)N)=O)(C(NCC(O)=O)=O)CSSSC[C@H](NC(CC[C@@H](C(O)=O)N)=O)C(NCC(O)=O)=O
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
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Glutathione trisulfide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Glutathione trisulfide32607-79-7GSSSGInterleukin RelatedERKILExtracellular signal regulated kinasesLPS-induced inflammatoryretinal pigment epithelial cellsERK signalingARPE-19ischemic injuryInhibitorinhibitorinhibit

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