Paf1 - Paf1, RNA polymerase II complex component Gene

Also Known as 5730511K23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54624

Summary

Enables chromatin binding activity. Involved in several processes, including cellular response to lipopolysaccharide; endodermal cell fate commitment; and negative regulation of transcription by RNA polymerase II. Part of Cdc73/Paf1 complex. Is expressed in cerebral cortex; early conceptus; and genitourinary system. Orthologous to human PAF1 (PAF1 homolog, Paf1/RNA polymerase II complex component). [provided by Alliance of Genome Resources, Apr 2022]

Paf1 Products (1)

mRNA Protein Name
NM_019458.3 NP_062331.2 RNA polymerase II-associated factor 1 homolog

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
22252316 MGI
contributes to protein binding IPI
IPI: Inferred from physical interaction
27749823 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
22252316 MGI
Biological Process GO Annotation Evidence References Source
involved in cellular response to lipopolysaccharide IDA
IDA: Inferred from direct assay
17911113 MGI
involved in endodermal cell fate commitment IMP
IMP: Inferred from mutant phenotype
19345177 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
19345177 MGI
involved in stem cell population maintenance IMP
IMP: Inferred from mutant phenotype
19345177 MGI
Cellular Component GO Annotation Evidence References Source
part of Cdc73/Paf1 complex IPI
IPI: Inferred from physical interaction
27749823 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RNA polymerase II-associated factor 1 homolog

  • Paf1, RNA polymerase II associated factor, homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-160267 iPAF1C 99.59% Unkown
HY-P3103A PINT-87aa TFA ≥99.0% Unkown
HY-130345S C18-PAF-d4 / Unkown
HY-170229 C17 Lyso PAF / Unkown
HY-N17414 Preschisanartanin O / Unkown
HY-N2247A (+)-Guaiacin / Unkown
HY-P3103 PINT-87aa / Unkown
HY-RS09966 PAF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10348 PEX2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-106062 CV 3988 Inhibitor / Unkown
HY-134235 PAF C-16 carboxylic acid / Unkown
HY-RS18363 Paf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21406 Pex2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24842 Paf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Paf1 NCBI NCBI:54623