2. Gene
  3. LAMTOR1 - late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 Gene

LAMTOR1 - late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as p18; PDRO; C11orf59; p27RF-Rho; Ragulator1

Gene ID: 55004 | Gene type: protein coding

About LAMTOR1

Cytogenetic location: 11q13.4 Genomic coordinates (GRCh38): 11:72,097,292-72,103,297 (from NCBI)

This gene has 8 transcripts (splice variants) and 204 orthologues. Ubiquitous expression in thyroid (RPKM 58.6), adrenal (RPKM 40.5) and 25 other tissues.

Summary

Enables GTPase binding activity. Contributes to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Involved in several processes, including Cholesterol homeostasis; positive regulation of TOR signaling; and regulation of Cholesterol transport. Located in lysosome. Part of Ragulator complex. [provided by Alliance of Genome Resources, Apr 2022]

LAMTOR1 Products(1)

mRNA Protein Name
NM_017907.3 NP_060377.1 ragulator complex protein LAMTOR1

LAMTOR1 Protein Structure

LAMTOR

LAMTOR: Late endosomal/lysosomal adaptor and MAPK and MTOR activator (16 - 88)

  • 0
  • 100
  • 161 a.a.
Protein Preferred Names Protein Names

ragulator complex protein LAMTOR1

RhoA activator C11orf59

Recombinant LAMTOR1 Proteins

Cat. No. Product Name Accession Purity
HY-P71583 LAMTOR1 Protein, Human (His) Q6IAA8 (2G-161P) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07513 LAMTOR1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus LAMTOR1 RGD RGD:735078
Bos taurus LAMTOR1 VGNC VGNC:30779
Felis catus LAMTOR1 VGNC VGNC:82041
Canis familiaris LAMTOR1 VGNC VGNC:42577
Macaca mulatta LAMTOR1 VGNC VGNC:74129
Mus musculus LAMTOR1 MGD MGI:1913758
Others LAMTOR1 NCBI