MIOX - myo-inositol oxygenase Gene

Also Known as ALDRL6

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55586

About MIOX

Cytogenetic location: 22q13.33 Genomic coordinates (GRCh38): 22:50,486,859-50,490,648 (from NCBI)

This gene has 4 transcripts (splice variants) and 194 orthologues. Restricted expression toward kidney (RPKM 162.3).

Summary

Enables ferric iron binding activity and inositol oxygenase activity. Involved in inositol catabolic process. Predicted to be located in cytoplasm and inclusion body. [provided by Alliance of Genome Resources, Apr 2022]

MIOX Products (1)

mRNA Protein Name
NM_017584.6 NP_060054.4 inositol oxygenase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables ferric iron binding IDA
IDA: Inferred from direct assay
18364358 GOA
enables inositol oxygenase activity IDA
IDA: Inferred from direct assay
18364358 GOA
Biological Process GO Annotation Evidence References Source
involved in inositol catabolic process IDA
IDA: Inferred from direct assay
18364358 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MIOX Protein Structure

MIOX

MIOX: Myo-inositol oxygenase (37 - 285)

  • 0
  • 100
  • 200
  • 285 a.a.
Protein Preferred Names Protein Names

inositol oxygenase

  • MI oxygenase

Related Diseases

Diseases Alias
Ichthyosis, Congenital, Autosomal Recessive 3

  • Autosomal Recessive Congenital Ichthyosis 3

  • ARCI3

  • Lamellar Ichthyosis 5

  • Collodion Baby, Self-Healing

  • Ichthyosis, Lamellar, 5, Formerly

  • Li5, Formerly

  • Li5

  • Self-Healing Collodion Baby

  • Ichthyosis, Congenital, Autosomal Recessive, Type 3
Hypoascorbemia

  • Scurvy

  • Ascorbic Acid Deficiency

  • Vitamin C Deficiency

  • Vitamin C, Inability To Synthesize

  • Deficiency Of Vitamin C

  • Scorbutus

  • Vitamin C
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08459 MIOX Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22235 Miox Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MIOX MGD MGI:1891725
Macaca mulatta MIOX VGNC VGNC:74769
Bos taurus MIOX VGNC VGNC:97286
Felis catus MIOX VGNC VGNC:63515
Canis familiaris MIOX VGNC VGNC:43240
Rattus norvegicus MIOX RGD RGD:628739
Others MIOX NCBI