2. Gene
  3. GSDMC - gasdermin C Gene

GSDMC - gasdermin C Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as MLZE

Gene ID: 56169 | Gene type: protein coding

About GSDMC

Cytogenetic location: 8q24.21 Genomic coordinates (GRCh38): 8:129,705,435-129,786,624 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele, 190 orthologues and 4 paralogues. Biased expression in skin (RPKM 9.5), spleen (RPKM 4.6) and 1 other tissue.

Summary

Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylserine binding activity. Predicted to be involved in defense response to bacterium and Pyroptosis. Predicted to act upstream of or within intestinal epithelial cell development. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

GSDMC Products(1)

mRNA Protein Name
NM_031415.3 NP_113603.1 gasdermin-C

GSDMC Protein Structure

Gasdermin

Gasdermin: Gasdermin family (4 - 484)

  • 0
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  • 508 a.a.
Protein Preferred Names Protein Names

gasdermin-C

melanoma-derived leucine zipper, extra-nuclear factor

Recombinant GSDMC Proteins

Cat. No. Product Name Accession Purity
HY-P71649 GSDMC Protein, Human (His-SUMO) Q9BYG8 (M1-A508) ≥95%

Related Diseases

Diseases Alias
Spinal Stenosis

Lumbar Spinal Stenosis

Cervical Spinal Stenosis

Spinal Stenosis Of Lumbar Region

Spinal Stenosis In Cervical Region

Spinal Canal Stenosis
Melanoma

Malignant Melanoma

Cutaneous Melanoma

Naevocarcinoma

Malignant Melanomas
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05856 GSDMC Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta GSDMC VGNC VGNC:73380
Rattus norvegicus GSDMC RGD RGD:1308989
Felis catus GSDMC VGNC VGNC:68276
Canis familiaris GSDMC VGNC VGNC:49925
Bos taurus GSDMC VGNC VGNC:29674
Others GSDMC NCBI