Acpp - acid phosphatase, prostate Gene
Also Known as Lap; PAP; Acp3; FRAP; Ppal; 5'-NT; A030005E02Rik
Species: Mus musculus
Summary
Enables thiamine phosphate Phosphatase activity. Involved in nucleobase-containing small molecule metabolic process; regulation of sensory perception of pain; and thiamine metabolic process. Located in filopodium; plasma membrane; and vesicle membrane. Is integral component of membrane. Is expressed in epithelium of phallic urethra of female; epithelium of phallic urethra of male; genital tubercle mesenchyme of female; and urethral plate. Used to study prostate Cancer. Human ortholog(s) of this gene implicated in prostate Cancer. Orthologous to human ACP3 (Acid Phosphatase 3). [provided by Alliance of Genome Resources, Apr 2022]
Acpp Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_019807.2 | NP_062781.2 | prostatic acid phosphatase isoform 2 precursor |
| NM_207668.2 | NP_997551.1 | prostatic acid phosphatase isoform 1 precursor |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables thiamine phosphate phosphatase activity |
IMP
IMP: Inferred from mutant phenotype
|
18940592 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in adenosine metabolic process |
IDA
IDA: Inferred from direct assay
|
18940592 | MGI |
| involved in nucleotide metabolic process |
IMP
IMP: Inferred from mutant phenotype
|
18940592 | MGI |
| involved in purine nucleobase metabolic process |
IMP
IMP: Inferred from mutant phenotype
|
18940592 | MGI |
| involved in regulation of sensory perception of pain |
IMP
IMP: Inferred from mutant phenotype
|
18940592 | MGI |
| involved in thiamine metabolic process |
IMP
IMP: Inferred from mutant phenotype
|
18940592 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in filopodium |
IDA
IDA: Inferred from direct assay
|
17658863 | MGI |
| located in membrane |
IDA
IDA: Inferred from direct assay
|
17658863 | MGI |
| located in plasma membrane |
IDA
IDA: Inferred from direct assay
|
17658863 | MGI |
| located in vesicle membrane |
IDA
IDA: Inferred from direct assay
|
18940592 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
prostatic acid phosphatase |
|
|
Recombinant Acpp Proteins
| Cat. No. | 상품명 | Accession | Purity |
|---|---|---|---|
| HY-P74430 | ACPP/Prostatic Acid Phosphatase Protein, Mouse (HEK293, His) | Q8CE08-2 (K32-R381) | ≥ 95%, as determined by reducing SDS-PAGE. |