Rps6ka4 - ribosomal protein S6 kinase, polypeptide 4 Gene

Also Known as Msk2; 90kDa; mMSK2; 1110069D02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56613

Summary

Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including histone-serine phosphorylation; interleukin-1-mediated signaling pathway; and positive regulation of histone modification. Predicted to act upstream of or within inflammatory response and phosphorylation. Predicted to be located in cytosol and nucleus. Predicted to be active in cytoplasm and nucleoplasm. Is expressed in 1st branchial arch maxillary component; heart; maxillary process; and sensory organ. Orthologous to human RPS6KA4 (ribosomal protein S6 kinase A4). [provided by Alliance of Genome Resources, Apr 2022]

Rps6ka4 Products (1)

mRNA Protein Name
NM_019924.2 NP_064308.2 ribosomal protein S6 kinase alpha-4

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15102471 MGI
Cellular Component GO Annotation Evidence References Source
is active in synapse EXP
EXP: Inferred from Experiment
25211037 MGI
is active in synapse IDA
IDA: Inferred from direct assay
25211037 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ribosomal protein S6 kinase alpha-4

  • 90 kDa ribosomal protein S6 kinase 4

  • RLSK

  • RSK-like protein kinase

  • S6K-alpha-4

  • mitogen- and stress-activated protein kinase-2

  • nuclear mitogen- and stress-activated protein kinase 2

  • ribosomal protein S6 kinase, 90kD, polypeptide 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-148065 FMF-06-098-1 Inhibitor 98.77% Unkown
HY-RS12257 RPS6KA4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22025 Rps6ka4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28543 Rps6ka4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rps6ka4 NCBI NCBI:8986