Lamtor3 - late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 Gene

Also Known as Mp1; Mapbp; Mapksp1; Map2k1ip1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56692

Summary

Enables kinase activator activity. Acts upstream of or within positive regulation of MAPK cascade and protein localization to cell junction. Located in late endosome. Is expressed in several structures, including central nervous system; genitourinary system; and retina. Orthologous to human LAMTOR3 (late endosomal/lysosomal adaptor, MAPK and mTOR Activator 3). [provided by Alliance of Genome Resources, Apr 2022]

Lamtor3 Products (1)

mRNA Protein Name
NM_019920.2 NP_064304.1 ragulator complex protein LAMTOR3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables kinase activator activity IDA
IDA: Inferred from direct assay
15263099 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15263099 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of MAPK cascade IDA
IDA: Inferred from direct assay
15263099 MGI
acts upstream of or within protein localization to cell junction IMP
IMP: Inferred from mutant phenotype
24841562 MGI
Cellular Component GO Annotation Evidence References Source
located in late endosome IDA
IDA: Inferred from direct assay
15263099 MGI
is active in late endosome IPI
IPI: Inferred from physical interaction
24841562 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ragulator complex protein LAMTOR3

  • MAPK scaffold protein 1

  • MEK binding partner 1

  • late endosomal/lysosomal adaptor and MAPK and MTOR activator 3

  • mitogen activated protein, binding protein

  • mitogen-activated protein kinase kinase 1-interacting protein 1

  • mitogen-activated protein kinase s

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07515 LAMTOR3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19090 Lamtor3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25580 Lamtor3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lamtor3 NCBI NCBI:8649