2. Gene
  3. PSG9 - pregnancy specific beta-1-glycoprotein 9 Gene

PSG9 - pregnancy specific beta-1-glycoprotein 9 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as PS34; PSG11; PSGII; PSBG-9; PSBG-11

Gene ID: 5678 | Gene type: protein coding

About PSG9

Cytogenetic location: 19q13.31 Genomic coordinates (GRCh38): 19:43,253,282-43,269,530 (from NCBI)

This gene has 9 transcripts (splice variants), 628 orthologues and 24 paralogues. Restricted expression toward placenta (RPKM 51.2).

Summary

The protein encoded by this gene is a member of the pregnancy-specific glycoprotein (PSG) family. This protein family and the closely related carcinoembryonic antigen cell adhesion molecule (CEACAM) gene family are both members of the immunoglobulin superfamily, and are organized as a large gene cluster. This protein is thought to inhibit platelet-fibrinogen interactions. Several studies suggest that reduced serum concentrations of PSGs are associated with fetal growth restrictions, while up-regulation of this gene has been observed in colorectal cancers. Several pseudogenes of this gene are found on chromosome 19. Alternative splicing results in multiple transcript variants that encode multiple protein isoforms. [provided by RefSeq, Sep 2014]

PSG9 Products(5)

mRNA Protein Name
NM_001301707.2 NP_001288636.1 pregnancy-specific beta-1-glycoprotein 9 isoform 2 precursor
NM_001301708.2 NP_001288637.1 pregnancy-specific beta-1-glycoprotein 9 isoform 3 precursor
NM_001301709.2 NP_001288638.1 pregnancy-specific beta-1-glycoprotein 9 isoform 4 precursor
NM_001411075.1 NP_001398004.1 pregnancy-specific beta-1-glycoprotein 9 isoform 5 precursor
NM_002784.5 NP_002775.3 pregnancy-specific beta-1-glycoprotein 9 isoform 1 precursor

PSG9 Protein Structure

V-set

V-set: Immunoglobulin V-set domain (39 - 130)

Ig_2

Ig_2: Immunoglobulin domain (149 - 234)

Ig_2

Ig_2: Immunoglobulin domain (253 - 328)

Ig_2

Ig_2: Immunoglobulin domain (335 - 413)

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  • 426 a.a.
Protein Preferred Names Protein Names

pregnancy-specific beta-1-glycoprotein 9

PS-beta-B

Recombinant PSG9 Proteins

Cat. No. Product Name Accession Purity
HY-P70984 PSG9 Protein, Human (HEK293, His) AAH20759.1 (E35-S426) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11288 PSG9 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Others PSG9 NCBI