IFNK - interferon kappa Gene

Also Known as IFNT1; INFE1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 56832

About IFNK

Cytogenetic location: 9p21.2 Genomic coordinates (GRCh38): 9:27,524,290-27,526,498 (from NCBI)

This gene has 1 transcript (splice variant), 141 orthologues and 16 paralogues. Low expression observed in reference dataset.

Summary

This gene encodes a member of the type I interferon family. Type I interferons are a group of related glycoproteins that play an important role in host defenses against viral infections. This protein is expressed in keratinocytes and the gene is found on chromosome 9, adjacent to the type I interferon cluster. [provided by RefSeq, Jul 2008]

IFNK Products (1)

mRNA Protein Name
NM_020124.3 NP_064509.2 interferon kappa precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables type I interferon receptor binding IDA
IDA: Inferred from direct assay
11514542 GOA
Biological Process GO Annotation Evidence References Source
involved in cytokine-mediated signaling pathway IDA
IDA: Inferred from direct assay
11514542 GOA
involved in regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
11514542 GOA
involved in response to virus IEP
IEP: Inferred from expression pattern
11514542 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IFNK Protein Structure

Interferon

Interferon: Interferon alpha/beta domain (41 - 205)

  • 0
  • 100
  • 207 a.a.
Protein Preferred Names Protein Names

interferon kappa

  • IFN-kappa

Related Diseases

Diseases Alias
Danubian Endemic Familial Nephropathy

  • Balkan Nephropathy

  • Balkan Endemic Nephropathy

  • Nephropathia Epidemica

  • Defn

  • Ben

  • Aristolochic Acid Nephropathy

  • Aan

  • Endemic Nephropathy Balkan

  • Balkan Nephritis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06590 IFNK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174661 Human IFNK mRNA / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus IFNK VGNC VGNC:62877
Canis familiaris IFNK VGNC VGNC:51739
Rattus norvegicus IFNK RGD RGD:1309045
Mus musculus IFNK MGD MGI:2683287
Bos taurus IFNK VGNC VGNC:30060
Others IFNK NCBI