2. Gene
  3. Cysltr1 - cysteinyl leukotriene receptor 1 Gene

Cysltr1 - cysteinyl leukotriene receptor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cyslt1; CysLT1R

Gene ID: 58861 | Gene type: protein coding

About Cysltr1

Chromosome X: 105,617,952-105,647,285 reverse strand.GRCm39:CM001013.3

This gene has 2 transcripts (splice variants), 177 orthologues, 16 paralogues and is associated with 10 phenotypes. Broad expression in placenta adult (RPKM 1.9), bladder adult (RPKM 1.) and 18 other tissues.

Summary

Enables Leukotriene Receptor activity. Acts upstream of or within several processes, including calcium ion transport; chemotaxis; and inflammatory response to antigenic stimulus. Is integral component of plasma membrane. Is expressed in central nervous system and retina. Human ortholog(s) of this gene implicated in allergic disease; asthma; and rhinitis. Orthologous to human CYSLTR1 (cysteinyl Leukotriene Receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Cysltr1 Products(3)

mRNA Protein Name
NM_001281859.1 NP_001268788.1 cysteinyl leukotriene receptor 1 isoform a
NM_001281862.1 NP_001268791.1 cysteinyl leukotriene receptor 1 isoform b
NM_021476.5 NP_067451.2 cysteinyl leukotriene receptor 1 isoform a

Cysltr1 Protein Structure

7tmA_CysLTR1

7tmA_CysLTR1: cd15158 (38 - 65)

7tmA_CysLTR1

7tmA_CysLTR1: cd15158 (38 - 320)

7tmA_CysLTR1

7tmA_CysLTR1: cd15158 (72 - 97)

7tmA_CysLTR1

7tmA_CysLTR1: cd15158 (110 - 140)

7tmA_CysLTR1

7tmA_CysLTR1: cd15158 (152 - 174)

7tmA_CysLTR1

7tmA_CysLTR1: cd15158 (200 - 229)

7tmA_CysLTR1

7tmA_CysLTR1: cd15158 (240 - 270)

7tmA_CysLTR1

7tmA_CysLTR1: cd15158 (288 - 313)

  • 0
  • 100
  • 200
  • 300
  • 352 a.a.
Protein Preferred Names Protein Names

cysteinyl leukotriene receptor 1

LTD4 receptor

cysteinyl leukotriene D4 receptor

Related Agents

Approval
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13315 Montelukast sodium Antagonist 99.52% Yes
HY-13315A Montelukast Antagonist 99.60% Yes
HY-13315B Montelukast dicyclohexylamine Antagonist / Unkown
Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13315S1 Montelukast-d6 sodium Antagonist ≥96.0% Unkown
HY-13315S Montelukast-d6 Antagonist / Unkown
HY-RS03494 CYSLTR1 Human Pre-designed siRNA Set A / Unkown
HY-RS03495 Cysltr1 Mouse Pre-designed siRNA Set A / Unkown
HY-RS03496 Cysltr1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cysltr1 NCBI NCBI:10800