FZD1 - Fzd1 frizzled class receptor 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 58868

Summary

Enables protein heterodimerization activity and protein homodimerization activity. Involved in several processes, including cellular response to vitamin D; lung alveolus development; and positive regulation of DNA-binding transcription factor activity. Located in neuron projection and plasma membrane. Orthologous to human FZD1 (Frizzled class receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

FZD1 Products (1)

mRNA Protein Name
NM_021266.3 NP_067089.2 frizzled-1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
14688793 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
14688793 RGD
enables protein heterodimerization activity IPI
IPI: Inferred from physical interaction
14688793 RGD
enables protein homodimerization activity IPI
IPI: Inferred from physical interaction
14688793 RGD
Biological Process GO Annotation Evidence References Source
involved in Wnt signaling pathway IDA
IDA: Inferred from direct assay
10559239 RGD
involved in canonical Wnt signaling pathway IDA
IDA: Inferred from direct assay
14688793 RGD
involved in cellular response to growth factor stimulus IEP
IEP: Inferred from expression pattern
1334084 RGD
involved in cellular response to peptide hormone stimulus IEP
IEP: Inferred from expression pattern
1334084 RGD
involved in cellular response to vitamin D IEP
IEP: Inferred from expression pattern
1334084 RGD
involved in lung alveolus development IEP
IEP: Inferred from expression pattern
17911382 RGD
involved in positive regulation of DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
14688793 RGD
involved in positive regulation of neuron projection development IDA
IDA: Inferred from direct assay
23825416 RGD
involved in regulation of osteoblast differentiation IEP
IEP: Inferred from expression pattern
1334084 RGD
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
14688793 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

frizzled-1

  • Drosophila polarity gene (frizzled) homologue

  • Drosophila polarity gene homolog 1

  • frizzled family receptor 1

  • fz-1

  • rFz1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P9974 Vantictumab Inhibitor 99.40% Phase 1

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05176 FZD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18358 Fzd1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24837 Fzd1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens FZD1 NCBI NCBI:8321