Usp14 - ubiquitin specific peptidase 14 Gene

Also Known as ax; nmf375; 2610005K12Rik; 2610037B11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 59025

Summary

Predicted to enable endopeptidase inhibitor activity; Proteasome binding activity; and thiol-dependent Deubiquitinase. Acts upstream of or within chemical synaptic transmission. Located in synapse. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and respiratory system. Orthologous to human USP14 (ubiquitin specific peptidase 14). [provided by Alliance of Genome Resources, Apr 2022]

Usp14 Products (3)

mRNA Protein Name
NM_001038589.2 NP_001033678.1 ubiquitin carboxyl-terminal hydrolase 14 isoform 2
NM_001360884.1 NP_001347813.1 ubiquitin carboxyl-terminal hydrolase 14 isoform 3
NM_021522.4 NP_067497.2 ubiquitin carboxyl-terminal hydrolase 14 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19135427 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
12368914 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
12368914 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
12368914 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
12368914 MGI
is active in presynaptic cytosol IDA
IDA: Inferred from direct assay
12368914 MGI
is active in presynaptic cytosol IEP
IEP: Inferred from expression pattern
12368914 MGI
is active in presynaptic cytosol IMP
IMP: Inferred from mutant phenotype
12368914 MGI
located in synapse IDA
IDA: Inferred from direct assay
12368914 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase 14

  • ataxia

  • dUB-type TGT for deubiquitinating enzyme

  • deubiquitinating enzyme 14

  • ubiquitin specific protease 14

  • ubiquitin thioesterase 14

  • ubiquitin thiolesterase 14

  • ubiquitin-specific-processing protease 14

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13264 Degrasyn 99.70% Unkown
HY-13817 IU1 99.30% Unkown
HY-13989 b-AP15 98.05% Unkown
HY-122243 IU1-47 Inhibitor 99.87% Unkown
HY-122885 IU1-248 Inhibitor 99.19% Unkown
HY-D1236 Fluorescent brightener 71 Inhibitor / Unkown
HY-135779 IU2-6 Inhibitor / Unkown
HY-164689 Cadmium pyrithione Inhibitor / Unkown
HY-176207 HDAC degrader-1 Degrader / Unkown
HY-181495 RAJQ14 Degrader / Unkown
HY-RS15525 USP14 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-15432 (E/Z)-NSC-687852 / Unkown
HY-RS16634 Usp14 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23069 Usp14 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Usp14 NCBI NCBI:9097