Kitlg - KIT ligand Gene

Also Known as Mgf; SCF; Kitl

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 60427

Summary

Predicted to enable cytokine activity and stem cell factor receptor binding activity. Involved in ovarian follicle development and positive regulation of cell population proliferation. Predicted to be located in several cellular components, including extracellular space; filopodium; and lamellipodium. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 69 and familial progressive hyperpigmentation with or without hypopigmentation. Orthologous to human KITLG (KIT ligand). [provided by Alliance of Genome Resources, Apr 2022]

Kitlg Products (2)

mRNA Protein Name
NM_021843.4 NP_068615.1 kit ligand isoform 1 precursor
NM_021844.2 NP_068616.1 kit ligand isoform 2 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in ovarian follicle development IDA
IDA: Inferred from direct assay
15062541 RGD
involved in positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
2208279 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
22777679 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kit ligand

  • C-kit ligand

  • hematopoietic growth factor KL

  • mast cell growth factor

  • steel factor/kit ligand

  • stem cell factor KL-1

Recombinant Kitlg Proteins

Cat. No. Product Name Accession Purity
HY-P7107 SCF Protein, Rat (P.pastoris) P21581-1 (Q26-A189) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P7107A SCF Protein, Rat (HEK293) P21581-1 (Q26-A189) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P71130 SCF Protein, Rat (HEK293, His) P21581-1 (Q26-A189) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P72480 SCF Protein, Rat (His) P21581-1 (Q26-A189) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07322 KITLG Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23875 Kitlg Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kitlg NCBI NCBI:4254