Wtap - WT1 associating protein Gene

Also Known as 2810408K05Rik; 9430038B09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 60532

Summary

Predicted to enable identical protein binding activity. Predicted to be involved in mRNA methylation and regulation of alternative mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Located in cytoplasm and nucleoplasm. Part of RNA N6-methyladenosine methyltransferase complex. Is expressed in several structures, including early conceptus; embryo mesoderm; genitourinary system; hemolymphoid system gland; and liver. Orthologous to human WTAP (WT1 associated protein). [provided by Alliance of Genome Resources, Apr 2022]

Wtap Products (4)

mRNA Protein Name
NM_001113532.1 NP_001107004.1 pre-mRNA-splicing regulator WTAP isoform b
NM_001113533.1 NP_001107005.1 pre-mRNA-splicing regulator WTAP isoform a
NM_001379058.1 NP_001365987.1 pre-mRNA-splicing regulator WTAP isoform a
NM_175394.2 NP_780603.1 pre-mRNA-splicing regulator WTAP isoform b

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12522145 MGI
Cellular Component GO Annotation Evidence References Source
part of RNA N6-methyladenosine methyltransferase complex IDA
IDA: Inferred from direct assay
29547716 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
29547716 MGI
located in nucleoplasm IDA
IDA: Inferred from direct assay
11001926 MGI
located in nucleus IDA
IDA: Inferred from direct assay
14681305 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pre-mRNA-splicing regulator WTAP

  • WT1-associated protein

  • Wilms tumour 1-associating protein

  • Wilms' tumour 1-associating protein

  • female-lethal(2)D homolog

  • wilms tumor 1-associating protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W037893 CHMA1004 dihydrochloride Activator 99.38% Unkown
HY-RS15854 WTAP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W125425 CHMA1004 Activator / Unkown
HY-RS17418 Wtap Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23872 Wtap Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Wtap NCBI NCBI:9589