Fhl2 - four and a half LIM domains 2 Gene

Also Known as SLIM 3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 63839

Summary

Predicted to enable bHLH transcription factor binding activity; identical protein binding activity; and transcription corepressor activity. Involved in negative regulation of calcineurin-NFAT signaling cascade. Located in M band and Z disc. Orthologous to human FHL2 (four and a half LIM domains 2). [provided by Alliance of Genome Resources, Apr 2022]

Fhl2 Products (2)

mRNA Protein Name
NM_001412599.1 NP_001399528.1 four and a half LIM domains protein 2
NM_031677.2 NP_113865.1 four and a half LIM domains protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16888242 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of calcineurin-NFAT signaling cascade IMP
IMP: Inferred from mutant phenotype
22851699 RGD
Cellular Component GO Annotation Evidence References Source
located in M band IDA
IDA: Inferred from direct assay
11062252 RGD
located in Z disc IDA
IDA: Inferred from direct assay
11062252 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

four and a half LIM domains protein 2

  • LIM domain protein DRAL

  • skeletal muscle LIM-protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04935 FHL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17638 Fhl2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24098 Fhl2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fhl2 NCBI NCBI:2274