PTGDR - prostaglandin D2 receptor Gene

Also Known as Ptgdr2; Ptgdrl

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 63889

About PTGDR

Primary_assembly 15: 17,360,304-17,367,679 forward strand.mRatBN7.2:CM026988.1

This gene has 1 transcript (splice variant), 116 orthologues and 8 paralogues.

Summary

Enables prostaglandin D receptor activity. Involved in negative regulation of cytosolic calcium ion concentration; positive regulation of penile erection; and vasodilation. Located in membrane. Human ortholog(s) of this gene implicated in asthma. Orthologous to human PTGDR (prostaglandin D2 receptor). [provided by Alliance of Genome Resources, Apr 2022]

PTGDR Products (1)

mRNA Protein Name
NM_022241.2 NP_071577.2 prostaglandin D2 receptor-like

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables prostaglandin D receptor activity IDA
IDA: Inferred from direct assay
10448933 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of cytosolic calcium ion concentration IMP
IMP: Inferred from mutant phenotype
19576888 RGD
involved in positive regulation of penile erection IDA
IDA: Inferred from direct assay
18047485 RGD
involved in vasodilation IMP
IMP: Inferred from mutant phenotype
17643322 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

prostaglandin D2 receptor-like

  • prostaglandin D receptor

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-15950 AZD1981 Antagonist 99.80% Phase 2

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11368 PTGDR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11369 Ptgdr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11370 PTGDR Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11371 PTGDR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11372 Ptgdr2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11373 Ptgdr2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PTGDR NCBI NCBI:5729