Ddah1 - dimethylarginine dimethylaminohydrolase 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64157

Summary

Enables amino acid binding activity and dimethylargininase activity. Involved in arginine metabolic process; positive regulation of angiogenesis; and positive regulation of nitric oxide biosynthetic process. Human ortholog(s) of this gene implicated in cardiovascular system disease and hypertension. Orthologous to human DDAH1 (dimethylarginine dimethylaminohydrolase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ddah1 Products (1)

mRNA Protein Name
NM_022297.3 NP_071633.1 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables amino acid binding IDA
IDA: Inferred from direct assay
17322279 RGD
enables dimethylargininase activity IDA
IDA: Inferred from direct assay
12237779 RGD
Biological Process GO Annotation Evidence References Source
involved in arginine metabolic process IDA
IDA: Inferred from direct assay
17322279 RGD
involved in positive regulation of angiogenesis IMP
IMP: Inferred from mutant phenotype
12237779 RGD
involved in positive regulation of nitric oxide biosynthetic process IMP
IMP: Inferred from mutant phenotype
12237779 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

N(G),N(G)-dimethylarginine dimethylaminohydrolase 1

  • DDAH-1

  • DDAHI

  • NG,NG dimethylarginine dimethylaminohydrolase

  • dimethylargininase-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-16958 PD 404182 Inhibitor 98.26% Unkown
HY-RS03604 DDAH1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19186 Ddah1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25674 Ddah1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ddah1 NCBI NCBI:23576