Foxb1 - forkhead box B1 Gene

Also Known as C43; Mf3; Twh; Fkh5; Foxb1a; Foxb1b; Hfh-e5.1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 64290

Summary

Enables sequence-specific DNA binding activity. Involved in several processes, including mammary gland development; nervous system development; and visual learning. Acts upstream of or within spinal cord development; thalamus development; and urogenital system development. Located in nucleus. Is expressed in several structures, including central nervous system; embryo ectoderm; limb; paraxial mesenchyme; and tail bud. Orthologous to human FOXB1 (forkhead box B1). [provided by Alliance of Genome Resources, Apr 2022]

Foxb1 Products (1)

mRNA Protein Name
NM_022378.3 NP_071773.2 forkhead box protein B1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
8306889 MGI
Biological Process GO Annotation Evidence References Source
involved in axon target recognition IMP
IMP: Inferred from mutant phenotype
10662642 MGI
involved in cell migration in diencephalon IMP
IMP: Inferred from mutant phenotype
19046377 MGI
involved in epithelial cell differentiation involved in mammary gland alveolus development IMP
IMP: Inferred from mutant phenotype
11170346 MGI
involved in floor plate development IMP
IMP: Inferred from mutant phenotype
18064677 MGI
involved in hypothalamus cell migration IMP
IMP: Inferred from mutant phenotype
19046377 MGI
involved in inferior colliculus development IMP
IMP: Inferred from mutant phenotype
11170346 MGI
involved in lactation IMP
IMP: Inferred from mutant phenotype
11170346 MGI
involved in mammary gland lobule development IMP
IMP: Inferred from mutant phenotype
11170346 MGI
involved in mammillary body development IEP
IEP: Inferred from expression pattern
11170346 MGI
involved in mammillary body development IMP
IMP: Inferred from mutant phenotype
15654859 MGI
involved in mammillothalamic axonal tract development IMP
IMP: Inferred from mutant phenotype
10662642 MGI
involved in midbrain development IMP
IMP: Inferred from mutant phenotype
11170346 MGI
involved in negative regulation of neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
10662642 MGI
involved in somitogenesis IMP
IMP: Inferred from mutant phenotype
18064677 MGI
involved in spinal cord development IEP
IEP: Inferred from expression pattern
11170346 MGI
involved in telencephalon cell migration IMP
IMP: Inferred from mutant phenotype
19046377 MGI
involved in thalamus development IEP
IEP: Inferred from expression pattern
11170346 MGI
involved in urogenital system development IEP
IEP: Inferred from expression pattern
11170346 MGI
involved in visual learning IMP
IMP: Inferred from mutant phenotype
15654859 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
8306889 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

forkhead box protein B1

  • forkhead box B1a

  • forkhead box B1b

  • mesoderm/mesenchyme forkhead 3

  • transcription factor FKH-5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05039 FOXB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22512 Foxb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29033 Foxb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Foxb1 NCBI NCBI:27023