Taok2 - TAO kinase 2 Gene

Also Known as Tao2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64666

Summary

Enables ATP binding activity and MAP kinase kinase kinase activity. Involved in MAPK cascade; basal dendrite arborization; and regulation of synaptic membrane adhesion. Is active in glutamatergic synapse. Orthologous to human TAOK2 (TAO kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Taok2 Products (1)

mRNA Protein Name
NM_022702.1 NP_073193.1 serine/threonine-protein kinase TAO2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATP binding IDA
IDA: Inferred from direct assay
15458637 RGD
enables MAP kinase kinase kinase activity IDA
IDA: Inferred from direct assay
10497253 RGD
Biological Process GO Annotation Evidence References Source
involved in MAPK cascade IDA
IDA: Inferred from direct assay
10497253 RGD
involved in basal dendrite arborization IGI
IGI: Inferred from genetic interaction
22683681 RGD
involved in basal dendrite morphogenesis IMP
IMP: Inferred from mutant phenotype
22683681 RGD
involved in regulation of postsynapse organization IDA
IDA: Inferred from direct assay
28065648 RGD
involved in regulation of postsynapse organization IMP
IMP: Inferred from mutant phenotype
28065648 RGD
involved in regulation of synaptic membrane adhesion IDA
IDA: Inferred from direct assay
17988630 RGD
involved in regulation of synaptic membrane adhesion IEP
IEP: Inferred from expression pattern
17988630 RGD
involved in regulation of synaptic membrane adhesion IMP
IMP: Inferred from mutant phenotype
17988630 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
17988630 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
17988630 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
28065648 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein kinase TAO2

  • serine-threonine kinase

  • thousand and one amino acid protein 2

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-100491 H3B-6527 Inhibitor 98.0% Phase 1

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-15141 Staurosporine 99.77% Unkown
HY-122232 SW083688 99.78% Unkown
HY-181280 VU6083859 Inhibitor / Unkown
HY-181281 VU6080195 Activator / Unkown
HY-RS14199 TAOK2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-181619 TAO Kinase-IN-3 Inhibitor / Unkown
HY-RS20110 Taok2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26614 Taok2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Taok2 NCBI NCBI:9344