Dpys - dihydropyrimidinase Gene

Also Known as DHP; DHPase; 1200017I10Rik; 1300004I01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 64705

Summary

Enables dihydropyrimidinase activity and phosphoprotein binding activity. Involved in pyrimidine nucleoside monophosphate catabolic process. Located in cytosol. Is expressed in cranium. Human ortholog(s) of this gene implicated in dihydropyrimidinase deficiency and purine-pyrimidine metabolic disorder. Orthologous to human DPYS (dihydropyrimidinase). [provided by Alliance of Genome Resources, Apr 2022]

Dpys Products (2)

mRNA Protein Name
NM_001164466.1 NP_001157938.1 dihydropyrimidinase
NM_022722.3 NP_073559.3 dihydropyrimidinase

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables dihydropyrimidinase activity IDA
IDA: Inferred from direct assay
5472365 MGI
enables phosphoprotein binding IPI
IPI: Inferred from physical interaction
10956643 MGI
Biological Process GO Annotation Evidence References Source
involved in CMP catabolic process IDA
IDA: Inferred from direct assay
5472365 MGI
involved in UMP catabolic process IDA
IDA: Inferred from direct assay
5472365 MGI
involved in dCMP catabolic process IDA
IDA: Inferred from direct assay
5472365 MGI
involved in dUMP catabolic process IDA
IDA: Inferred from direct assay
5472365 MGI
Cellular Component GO Annotation Evidence References Source
is active in cytosol IDA
IDA: Inferred from direct assay
5472365 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dihydropyrimidinase

  • dihydropyrimidine amidohydrolase

  • hydantoinase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03976 DPY19L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03977 DPY19L3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03978 DPY30 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03980 DPYS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20718 Dpys Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20912 Dpy30 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27229 Dpys Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27429 Dpy30 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27430 Duox2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dpys NCBI NCBI:1807