Dpys - dihydropyrimidinase Gene

Also Known as DHP

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 65135

Summary

Enables several functions, including dihydropyrimidinase activity; pyrimidine nucleobase binding activity; and zinc ion binding activity. Involved in beta-alanine metabolic process; thymine catabolic process; and uracil catabolic process. Located in cytosol. Part of protein-containing complex. Human ortholog(s) of this gene implicated in dihydropyrimidinase deficiency and purine-pyrimidine metabolic disorder. Orthologous to human DPYS (dihydropyrimidinase). [provided by Alliance of Genome Resources, Apr 2022]

Dpys Products (1)

mRNA Protein Name
NM_031705.2 NP_113893.2 dihydropyrimidinase

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables amino acid binding IDA
IDA: Inferred from direct assay
8307005 RGD
enables dihydropyrimidinase activity IDA
IDA: Inferred from direct assay
7626590 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
8307005 RGD
enables thymine binding IDA
IDA: Inferred from direct assay
8307005 RGD
enables uracil binding IDA
IDA: Inferred from direct assay
8307005 RGD
enables zinc ion binding IDA
IDA: Inferred from direct assay
8307005 RGD
enables zinc ion binding IMP
IMP: Inferred from mutant phenotype
7626590 RGD
Biological Process GO Annotation Evidence References Source
involved in beta-alanine metabolic process IDA
IDA: Inferred from direct assay
8307005 RGD
involved in thymine catabolic process IDA
IDA: Inferred from direct assay
8307005 RGD
involved in uracil catabolic process IDA
IDA: Inferred from direct assay
8307005 RGD
involved in uracil metabolic process IDA
IDA: Inferred from direct assay
7626590 RGD
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
8307005 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
8307005 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dihydropyrimidinase

  • DHPase

  • dihydropyrimidine amidohydrolase

  • hydantoinase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03976 DPY19L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03977 DPY19L3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03978 DPY30 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03980 DPYS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20718 Dpys Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20912 Dpy30 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27229 Dpys Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27429 Dpy30 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27430 Duox2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dpys NCBI NCBI:1807