Sdhc - succinate dehydrogenase complex, subunit C, integral membrane protein Gene

Also Known as 0610010E03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66052

Summary

Predicted to enable electron transfer activity; metal ion binding activity; and Succinate Dehydrogenase activity. Predicted to be involved in mitochondrial electron transport, succinate to ubiquinone. Predicted to act upstream of or within tricarboxylic acid cycle. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Used to study Leigh disease. Human ortholog(s) of this gene implicated in Carney-Stratakis syndrome; gastrointestinal stromal tumor; lung non-small cell carcinoma; and paraganglioma. Orthologous to human SDHC (Succinate Dehydrogenase complex subunit C). [provided by Alliance of Genome Resources, Apr 2022]

Sdhc Products (1)

mRNA Protein Name
NM_025321.3 NP_079597.2 succinate dehydrogenase cytochrome b560 subunit, mitochondrial precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
16120479 MGI
part of respiratory chain complex II (succinate dehydrogenase) IDA
IDA: Inferred from direct assay
16120479 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

succinate dehydrogenase cytochrome b560 subunit, mitochondrial

  • QPs-1

  • QPs1

  • integral membrane protein CII-3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-180107 H36-E4 Inhibitor 98.57% Unkown
HY-180108 H111-H7 Inhibitor 98.14% Unkown
HY-178495 SDH-IN-36 / Unkown
HY-RS12594 SDHC Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21430 Sdhc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27948 Sdhc Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sdhc NCBI NCBI:6391