Alg13 - asparagine-linked glycosylation 13 Gene

Also Known as MDS031; Glt28d1; 2810046O15Rik; 4833435D08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67574

Summary

Predicted to enable N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity and thiol-dependent Deubiquitinase. Acts upstream of or within negative regulation of TORC1 signaling; negative regulation of neuron death; and regulation of synaptic plasticity. Located in cytoplasm. Is expressed in several structures, including forelimb bud; nervous system; and respiratory system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 36. Orthologous to human ALG13 (ALG13 UDP-N-acetylglucosaminyltransferase subunit). [provided by Alliance of Genome Resources, Apr 2022]

Alg13 Products (1)

mRNA Protein Name
NM_026247.3 NP_080523.2 putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of TORC1 signaling IMP
IMP: Inferred from mutant phenotype
30872163 MGI
acts upstream of or within regulation of synaptic plasticity IMP
IMP: Inferred from mutant phenotype
30872163 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
30872163 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13

  • UDP-N-acetylglucosamine transferase subunit ALG13 homolog

  • asparagine-linked glycosylation 13 homolog

  • glycosyltransferase 28 domain containing 1

  • glycosyltransferase 28 domain-containing protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS22385 Alg13 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00590 ALG13 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28909 Alg13 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Alg13 NCBI NCBI:79868