Nmb - neuromedin B Gene

Also Known as 3110023K12Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68039

Summary

This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in satiety, reproduction and thermoregulation, as well as in stress, fear and Other behavioral responses. This gene encodes distinct isoforms, some or all of which may undergo similar processing to generate the mature protein. [provided by RefSeq, Sep 2016]

Nmb Products (2)

mRNA Protein Name
NM_001291280.1 NP_001278209.1 neuromedin-B isoform 1 preproprotein
NM_026523.4 NP_080799.1 neuromedin-B isoform 2 preproprotein

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in antiviral innate immune response IDA
IDA: Inferred from direct assay
31601264 MGI
involved in negative regulation of interleukin-6 production IMP
IMP: Inferred from mutant phenotype
31601264 MGI
involved in positive regulation of interferon-alpha production IDA
IDA: Inferred from direct assay
31601264 MGI
involved in positive regulation of osteoclast proliferation IMP
IMP: Inferred from mutant phenotype
28780306 MGI
involved in positive regulation of respiratory gaseous exchange IDA
IDA: Inferred from direct assay
26855425 MGI
involved in sensory perception of itch IDA
IDA: Inferred from direct assay
30734045 MGI
involved in sneeze reflex IMP
IMP: Inferred from mutant phenotype
34133943 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
34133943 MGI
located in neuron projection IDA
IDA: Inferred from direct assay
26855425 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuromedin-B

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-141604 Glembatumumab vedotin Inhibitor ≥99.0% Phase 2

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P0241 Neuromedin B 99.22% Unkown
HY-116216 PD 168368 Antagonist ≥99.0% Unkown
HY-N2600 Kuwanon H 98.60% Unkown
HY-103277A BIM 23042 TFA Antagonist 99.75% Unkown
HY-RS05648 GPNMB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09368 NMB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-103277 BIM 23042 Antagonist / Unkown
HY-125075 PD 165929 Antagonist / Unkown
HY-17674 Bombesin receptor antagonist-1 Antagonist / Unkown
HY-N2600R Kuwanon H (Standard) / Unkown
HY-RS17137 Nmb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23583 Nmb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992424 NMB04 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nmb NCBI NCBI:4828