Ifitm1 - interferon induced transmembrane protein 1 Gene

Also Known as Mil2; Mil-2; DSPA2a; 1110036C17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68713

Summary

Involved in response to virus. Acts upstream of or within defense response to virus; negative regulation of viral entry into host cell; and somitogenesis. Predicted to be located in early endosome and lysosomal membrane. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; extraembryonic component; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in adenosquamous gallbladder carcinoma and gallbladder adenocarcinoma. Orthologous to human IFITM1 (interferon induced transmembrane protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Ifitm1 Products (4)

mRNA Protein Name
NM_001112715.1 NP_001106186.1 interferon-induced transmembrane protein 1 isoform a
NM_001360727.1 NP_001347656.1 interferon-induced transmembrane protein 1 isoform a
NM_001360728.1 NP_001347657.1 interferon-induced transmembrane protein 1 isoform b
NM_026820.3 NP_081096.3 interferon-induced transmembrane protein 1 isoform a

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within anterior/posterior pattern specification IMP
IMP: Inferred from mutant phenotype
15857914 MGI
acts upstream of or within defense response to virus IDA
IDA: Inferred from direct assay
20064371 MGI
acts upstream of or within negative regulation of viral entry into host cell IDA
IDA: Inferred from direct assay
25738301 MGI
involved in negative regulation of viral entry into host cell IDA
IDA: Inferred from direct assay
21253575 MGI
involved in response to virus IDA
IDA: Inferred from direct assay
21253575 MGI
acts upstream of or within somitogenesis IMP
IMP: Inferred from mutant phenotype
15857914 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interferon-induced transmembrane protein 1

  • dispanin subfamily A member 2a

  • fragilis protein 2

  • fragilis2

  • ifitm-like protein 2

  • interferon induced transmembrane protein 2 like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-155815 MS9715 99.48% Unkown
HY-RS06565 IFITM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20165 Ifitm1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26669 Ifitm1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ifitm1 NCBI NCBI:8519