Rreb1 - ras responsive element binding protein 1 Gene

Also Known as 1110037N09Rik; B930013M22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68750

Summary

Enables DNA-binding transcription factor activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of brown fat cell differentiation. Acts upstream of or within negative regulation of transcription, DNA-templated. Predicted to be located in fibrillar center and nuclear speck. Predicted to be active in nucleus. Is expressed in central nervous system; genitourinary system; and pancreas epithelium. Orthologous to human RREB1 (Ras responsive element binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Rreb1 Products (8)

mRNA Protein Name
NM_001039188.2 NP_001034277.1 ras-responsive element-binding protein 1 isoform 1
NM_001177868.2 NP_001171339.1 ras-responsive element-binding protein 1 isoform 1
NM_001177869.2 NP_001171340.1 ras-responsive element-binding protein 1 isoform 2
NM_001404757.1 NP_001391686.1 ras-responsive element-binding protein 1 isoform 3
NM_001404758.1 NP_001391687.1 ras-responsive element-binding protein 1 isoform 3
NM_001404759.1 NP_001391688.1 ras-responsive element-binding protein 1 isoform 4
NM_001404760.1 NP_001391689.1 ras-responsive element-binding protein 1 isoform 4
NM_026830.3 NP_081106.1 ras-responsive element-binding protein 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
21159816 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
21159816 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
20133935 MGI
involved in positive regulation of brown fat cell differentiation IMP
IMP: Inferred from mutant phenotype
27923061 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-responsive element-binding protein 1

  • RAS-responsive zinc finger transcription factor RREB

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12283 RREB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21041 Rreb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27559 Rreb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rreb1 NCBI NCBI:6239