Ppil1 - peptidylprolyl isomerase (cyclophilin)-like 1 Gene

Predicted to enable cyclosporin A binding activity; disordered domain specific binding activity; and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in mRNA splicing, via spliceosome and protein peptidyl-prolyl isomerization. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be part of U2-type catalytic step 2 spliceosome. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; respiratory system; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia. Orthologous to human PPIL1 (peptidylprolyl isomerase like 1). [provided by Alliance of Genome Resources, Apr 2022]