Tcap - titin-cap Gene

Predicted to enable several functions, including BMP binding activity; cytoskeletal protein binding activity; and titin Z domain binding activity. Predicted to be a structural constituent of muscle. Predicted to be involved in several processes, including cardiac muscle hypertrophy in response to stress; myofibril assembly; and striated muscle contraction. Predicted to act upstream of or within adult heart development; otic vesicle formation; and somitogenesis. Predicted to be located in Z disc. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2G and hypertrophic cardiomyopathy 25. Orthologous to human TCAP (titin-cap). [provided by Alliance of Genome Resources, Apr 2022]