Ccl1 - C-C motif chemokine ligand 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 688605

Summary

Predicted to enable CCR Chemokine Receptor binding activity and chemokine activity. Involved in response to glucocorticoid. Predicted to be active in extracellular space. Biomarker of glomerulonephritis and nephrosis. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease; multiple sclerosis; pulmonary tuberculosis; and tuberculosis. Orthologous to human CCL1 (C-C motif chemokine ligand 1). [provided by Alliance of Genome Resources, Apr 2022]

Ccl1 Products (1)

mRNA Protein Name
NM_001191092.1 NP_001178021.1 C-C motif chemokine 1 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in response to glucocorticoid IEP
IEP: Inferred from expression pattern
11157384 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-C motif chemokine 1

  • chemokine (C-C motif) ligand 1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P990914 Denikitug 99.00% Phase 2
HY-P991944 ZL-1218 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-122219 R243 Antagonist 98.09% Unkown
HY-124416 ML604086 Inhibitor 99.78% Unkown
HY-144197 CCR8 antagonist 1 Antagonist 99.50% Unkown
HY-RS02080 CCL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174772 Human CCL1 mRNA / Unkown
HY-RS16818 Ccl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23259 Ccl1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccl1 NCBI NCBI:6346