Setd7 - SET domain containing 7, histone lysine methyltransferase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 689954

Summary

Enables chromatin binding activity. Involved in positive regulation of transcription, DNA-templated and response to ethanol. Located in nucleus. Used to study extrahepatic cholestasis. Orthologous to human SETD7 (SET domain containing 7, histone lysine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Setd7 Products (1)

mRNA Protein Name
NM_001109558.1 NP_001103028.1 histone-lysine N-methyltransferase SETD7

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
20930066 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
20930066 RGD
involved in response to alcohol IEP
IEP: Inferred from expression pattern
26509893 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
23413810 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

histone-lysine N-methyltransferase SETD7

  • SET domain containing (lysine methyltransferase) 7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-18627A PFI-2 hydrochloride Inhibitor 99.48% Unkown
HY-13807 UNC0646 Inhibitor 99.38% Unkown
HY-18627 PFI-2 Inhibitor 99.68% Unkown
HY-110196 (S)-PFI-2 hydrochloride Inhibitor / Unkown
HY-119164 DC-S238 Inhibitor / Unkown
HY-156455 SETD7-IN-1 Inhibitor / Unkown
HY-182676 DC541 Inhibitor / Unkown
HY-RS12747 SETD7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18842 Setd7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25334 Setd7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Setd7 NCBI NCBI:80854