Ddah1 - dimethylarginine dimethylaminohydrolase 1 Gene

Also Known as 2410006N07Rik; 2510015N06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69219

Summary

Enables dimethylargininase activity. Involved in positive regulation of nitric oxide biosynthetic process and regulation of systemic arterial blood pressure. Located in mitochondrion. Is expressed in several structures, including brain; cardiovascular system; future prosencephalon; retina; and spinal cord. Human ortholog(s) of this gene implicated in cardiovascular system disease and hypertension. Orthologous to human DDAH1 (dimethylarginine dimethylaminohydrolase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ddah1 Products (1)

mRNA Protein Name
NM_026993.3 NP_081269.1 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables dimethylargininase activity IMP
IMP: Inferred from mutant phenotype
21493890 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of nitric oxide biosynthetic process IMP
IMP: Inferred from mutant phenotype
21493890 MGI
involved in regulation of systemic arterial blood pressure IMP
IMP: Inferred from mutant phenotype
21493890 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

N(G),N(G)-dimethylarginine dimethylaminohydrolase 1

  • DDAH-1

  • DDAHI

  • dimethylargininase-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-16958 PD 404182 Inhibitor 98.26% Unkown
HY-RS03604 DDAH1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19186 Ddah1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25674 Ddah1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ddah1 NCBI NCBI:23576