Pxdn - peroxidasin Gene

Also Known as VPO1; mKIAA0230; E330004E07; 2310075M15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69675

Summary

Predicted to enable bromide peroxidase activity and heme binding activity. Predicted to be an extracellular matrix structural constituent. Involved in extracellular matrix organization. Located in collagen-containing extracellular matrix. Is expressed in several structures, including branchial arch; central nervous system; gut; heart; and sensory organ. Human ortholog(s) of this gene implicated in anterior segment dysgenesis 7. Orthologous to human PXDN (peroxidasin). [provided by Alliance of Genome Resources, Apr 2022]

Pxdn Products (1)

mRNA Protein Name
NM_181395.2 NP_852060.2 peroxidasin homolog precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables oxidoreductase activity, acting on peroxide as acceptor IDA
IDA: Inferred from direct assay
22842973 MGI
enables oxidoreductase activity, acting on peroxide as acceptor IMP
IMP: Inferred from mutant phenotype
32571911 MGI
Biological Process GO Annotation Evidence Verweise Source
involved in basement membrane assembly IDA
IDA: Inferred from direct assay
22842973 MGI
involved in basement membrane assembly IMP
IMP: Inferred from mutant phenotype
25708780 MGI
involved in basement membrane organization IMP
IMP: Inferred from mutant phenotype
24895407 MGI
involved in cell adhesion IMP
IMP: Inferred from mutant phenotype
24895407 MGI
involved in extracellular matrix organization IDA
IDA: Inferred from direct assay
19590037 MGI
involved in eye development IMP
IMP: Inferred from mutant phenotype
31817535 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in basement membrane IDA
IDA: Inferred from direct assay
22842973 MGI
located in collagen-containing extracellular matrix IDA
IDA: Inferred from direct assay
19590037 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peroxidasin homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS11479 PXDN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20331 Pxdn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26839 Pxdn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pxdn NCBI NCBI:7837