Pgrmc2 - progesterone receptor membrane component 2 Gene

Also Known as DG6; PMBP; 4631434O19Rik; 5730409G06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 70804

Summary

Enables heme binding activity and heme transmembrane transporter activity. Involved in heme transport. Predicted to be located in endoplasmic reticulum and nuclear envelope. Predicted to be active in endomembrane system and membrane. Is expressed in several structures, including central nervous system; neural retina; pharyngo-tympanic tube; and submandibular gland primordium. Orthologous to human PGRMC2 (Progesterone Receptor membrane component 2). [provided by Alliance of Genome Resources, Apr 2022]

Pgrmc2 Products (1)

mRNA Protein Name
NM_027558.1 NP_081834.1 membrane-associated progesterone receptor component 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables heme binding IDA
IDA: Inferred from direct assay
31748741 MGI
enables heme transmembrane transporter activity IDA
IDA: Inferred from direct assay
31748741 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11591653 MGI
Biological Process GO Annotation Evidence References Source
involved in heme transport IDA
IDA: Inferred from direct assay
31748741 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
31171447 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
31171447 MGI
is active in synapse IDA
IDA: Inferred from direct assay
31171447 MGI
is active in synapse IMP
IMP: Inferred from mutant phenotype
31171447 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

membrane-associated progesterone receptor component 2

  • progesterone membrane binding protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-115625 AG-205 99% Unkown
HY-186011 CPAG-1 Activator / Unkown
HY-RS10400 PGRMC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21906 Pgrmc2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28423 Pgrmc2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pgrmc2 NCBI NCBI:10424