Hbp1 - high mobility group box transcription factor 1 Gene

Also Known as 1700058O05Rik; C330012F01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 73389

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of lipid transport and negative regulation of Reactive Oxygen Species biosynthetic process. Predicted to be located in nuclear speck. Predicted to be active in nucleus. Is expressed in several structures, including brain; early conceptus; genitourinary system; gut; and neural retina. Orthologous to human HBP1 (HMG-box transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Hbp1 Products (3)

mRNA Protein Name
NM_001361928.1 NP_001348857.1 HMG box-containing protein 1 isoform 3
NM_153198.3 NP_694878.2 HMG box-containing protein 1 isoform 1
NM_177993.4 NP_818774.2 HMG box-containing protein 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
9178770 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of lipid transport IDA
IDA: Inferred from direct assay
24675724 MGI
involved in negative regulation of reactive oxygen species biosynthetic process IDA
IDA: Inferred from direct assay
24675724 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

HMG box-containing protein 1

  • HMG box transcription factor 1

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B1165 Cyproheptadine (hydrochloride sesquihydrate) 99.74% Unkown

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06033 HBP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18616 Hbp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25102 Hbp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hbp1 NCBI NCBI:26959