Pank1 - pantothenate kinase 1 Gene

Also Known as Pank; Pank1b

Species: Mus musculus

Gene Type: protein coding
Gene ID: 75735

Summary

Enables pantothenate kinase activity. Acts upstream of or within coenzyme A biosynthetic process. Located in several cellular components, including cytosol; nucleus; and recycling endosome. Part of clathrin coat. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human PANK1 (pantothenate kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Pank1 Products (2)

mRNA Protein Name
NM_001114339.2 NP_001107811.1 pantothenate kinase 1 isoform 1
NM_023792.2 NP_076281.1 pantothenate kinase 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables pantothenate kinase activity IDA
IDA: Inferred from direct assay
10625688 MGI
enables pantothenate kinase activity IGI
IGI: Inferred from genetic interaction
22815849 MGI
enables pantothenate kinase activity IMP
IMP: Inferred from mutant phenotype
10625688 MGI
Biological Process GO Annotation Evidence References Source
involved in coenzyme A biosynthetic process IDA
IDA: Inferred from direct assay
10625688 MGI
involved in coenzyme A biosynthetic process IGI
IGI: Inferred from genetic interaction
22815849 MGI
acts upstream of or within coenzyme A biosynthetic process IMP
IMP: Inferred from mutant phenotype
20559429 MGI
Cellular Component GO Annotation Evidence References Source
located in cell periphery IDA
IDA: Inferred from direct assay
22072979 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
16040613 MGI
is active in cytosol IDA
IDA: Inferred from direct assay
10625688 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pantothenate kinase 1

  • pantothenic acid kinase 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-44170 Pantothenate kinase-IN-2 Inhibitor 98.18% Unkown
HY-159509 Claziprotamidum Modulator 98.33% Unkown
HY-181917 Pantothenate kinase-IN-3 Activator / Unkown
HY-181256 PANK1/3 activator 1 Activator / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pank1 NCBI NCBI:53354