Abcc3 - ATP-binding cassette, sub-family C (CFTR/MRP), member 3 Gene

Also Known as MLP2; MRP3; ABC31; MOAT-D; 1700019L09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76408

Summary

Predicted to enable ABC-type transporter activity; glucuronoside transmembrane transporter activity; and icosanoid transmembrane transporter activity. Predicted to be involved in anion transport and xenobiotic transmembrane transport. Predicted to act upstream of or within canalicular bile acid transport. Located in basolateral plasma membrane. Is integral component of plasma membrane. Is expressed in alimentary system; liver; and small intestine. Orthologous to human ABCC3 (ATP binding cassette subfamily C member 3). [provided by Alliance of Genome Resources, Apr 2022]

Abcc3 Products (3)

mRNA Protein Name
NM_001363187.1 NP_001350116.1 ATP-binding cassette sub-family C member 3 isoform 1
NM_001363189.1 NP_001350118.1 ATP-binding cassette sub-family C member 3 isoform 3
NM_029600.4 NP_083876.3 ATP-binding cassette sub-family C member 3 isoform 2

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
16225954 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
12951053 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ATP-binding cassette sub-family C member 3

  • ATP-binding cassette protein C3

  • ATP-binding cassette transporter

  • canalicular multispecific organic anion transporter 2

  • multidrug resistance-associated protein 3

  • transporter

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0488A Vincristine 98.60% Yes

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N2382 Polyphyllin H Inhibitor 99.89% Unkown
HY-RS00062 ABCC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19977 Abcc3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26480 Abcc3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abcc3 NCBI NCBI:8714